Unleashing the Power of AI and Genome Editing for Food Security

TL;DR:

  • Food production strains the climate and environment, while extreme weather threatens food security.
  • AI and CRISPR-CAS9 gene editing can develop climate-resistant crops for higher yields with fewer resources.
  • Gene-edited rice shows promise in drought resistance with reduced water consumption.
  • Genome editing differs from traditional genetic engineering, offering precise modifications with controlled mutation processes.
  • AI enables rapid data processing and identification of optimization opportunities in genes for crop enhancement.
  • Gene-edited plant research is on the rise globally, with substantial investments and a burgeoning market.
  • Conventional breeding remains essential alongside emerging techniques for global food security.

Main AI News:

Addressing the challenge of food production poses a significant strain on our climate and environment. Moreover, the escalating risk of crop failures caused by extreme weather events threatens the food security of an ever-expanding global population. According to a recent report by the World Resource Institute (WRI), the world needs to bridge a 50% gap between current food production and the requirements of adequately feeding people by 2050. Astonishingly, this has to be achieved without further exploitation of resources and land. Janet Ranganathan, a nutrition expert at WRI and co-author of the report, states that expanding the agricultural frontier would mean sacrificing the remaining natural ecosystems. Finding a viable solution becomes paramount.

A potential avenue to confront this formidable challenge lies in repurposing the land currently dedicated to meat production and animal feed crops for the cultivation of plants suitable for human consumption. However, expecting everyone to adopt a vegetarian lifestyle remains an unrealistic scenario. This is where artificial intelligence (AI) steps in.

Could drought-resistant rice paddy fields become a reality in the near future? Scientists are exploring the use of AI and the revolutionary CRISPR-CAS9 gene-editing technique to develop climate-resistant supercultures capable of yielding higher output with fewer resources. This is achieved through the modification of plants’ genes, a process known as genome editing.

Rice presents an ideal platform for experimentation. Traditionally, rice, a water-intensive crop, has suffered greatly from extreme droughts, impacting regions from Italy to China and Pakistan. However, a new variety known as IR64 shows promise. While it predominantly grows in Asia and parts of Africa, it is widely available worldwide. Through gene modification, this strain of rice has become more drought-resistant, necessitating up to 40% less water compared to its predecessor. Moreover, when faced with water scarcity, half of the genetically modified plants survived, while the unmodified mother plant perished.

What distinguishes genome editing from traditional genetic engineering is its reliance on natural processes, albeit with a more controlled and less random mutation process. Detlef Weigel, a biologist at the Max Planck Society in Germany, explains that gene editing enables modifications of the genetic code using the organism’s own DNA. Utilizing specialized enzymes functioning as molecular scissors, specific genes within a plant can be removed, replaced, or duplicated. The natural crossing method, on the other hand, would require numerous breeding generations to transfer a single gene—an impractical time frame. Weigel emphasizes the tremendous power of genome editing, enabling precise alterations in single genes to achieve desired outcomes swiftly.

While traditional crossbreeding may take over a decade to obtain the desired results, gene editing accomplishes the same within a few months, with a few additional years required for testing and validation. Nonetheless, the implementation of gene editing techniques is not without risks and uncertainties. As many ongoing projects are still in the research phase, the lack of sufficient data raises concerns. Opponents of genetic research argue that gene editing poses a dangerous experiment with nature, pointing to cases where unintended genetic changes occurred or where more genetic information was inadvertently deleted. Additionally, certain genes that enhance yields during drought conditions can adversely affect productivity during wet years. Given the complex interplay of numerous genes involved in these traits, merely activating or deactivating one or two is often inadequate.

Artificial intelligence could play a crucial role in addressing these challenges. The less optimized a crop is, the greater the potential for improvement. Consequently, the CRISPR technique holds tremendous promise for enhancing the productivity of ancient crop varieties that have yet to undergo industrial-scale cultivation and breeding. Phytoform, a pioneering startup, leverages artificial intelligence to identify optimization opportunities within genes. By rapidly processing vast volumes of data, Phytoform’s algorithms surpass human capabilities, comprehending DNA datasets and suggesting meaningful changes to achieve desired outcomes. The company’s ongoing endeavors involve developing a non-browning potato that reduces food waste and enhances lupines, a protein-rich crop with immense potential in plant-based meat production.

Research into gene-edited plants is rapidly accelerating worldwide. From just a few patents filed in 2011, the number surged to nearly 2,000 by 2019, with private companies and public research institutions leading the charge. The United States, China, and multinational corporations have invested heavily in this technology, and it is expected to generate a multi-billion dollar market by the end of the decade. While the European Union strictly regulates gene-edited crops, labeling them as gene-modified, proponents argue that this classification overlooks the fact that it represents a new breeding method rather than genetic manipulation. In contrast, the United States, China, and many Latin American countries do not require labeling or control of genome-edited crops, with numerous new crops set to be introduced in the coming years. India has also recently eased its regulations.

Regardless of regulatory frameworks and the advancements made through cutting-edge methods, conventional breeding will continue to be indispensable in ensuring global food security. Collaborative efforts between traditional and emerging techniques will pave the way for a sustainable future, wherein AI and genome editing coexist to tackle the challenges of nourishing a growing population.

Conclusion:

The utilization of AI and genome editing in agriculture represents a revolutionary approach to addressing the pressing challenges of food security. By leveraging advanced technologies and precise genetic modifications, researchers are developing climate-resistant crops that offer higher yields with reduced resource consumption. The market for gene-edited crops is set to grow significantly, with notable investments from major players. However, it is crucial to recognize the importance of maintaining a balanced approach by combining conventional breeding methods with emerging techniques. Collaboration between traditional and innovative approaches will be vital for ensuring sustainable and resilient food production in the future.

Source